'A murrain on you' definitions:

Definition of 'A murrain on you'

From: GCIDE

Murrain \Mur"rain\, n. [OE. moreine, OF. morine, fr. OF. morir, murir, 8die, L. mori, moriri.] (Far.) An infectious and fatal disease among cattle. --Bacon. [1913 Webster]
A murrain on you, may you be afflicted with a pestilent disease. --Shak. [1913 Webster]

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