dna ligase

1 definition found

dna ligase - Collaborative International Dictionary of English v.0.48 :

  ligase \ligase\ n. (Biochem.)
     An enzyme which catalyzes creation of a covalent bond between
     two substrates, resulting in a larger product which is a
     combination of the two starting materials; especially, DNA ligase
     , an enzyme which creates a phosphate bond between 5'
     and 3' ends of a DNA chain, resulting in a longer chain of
     DNA. DNA ligase is important in normal biosynthesis of DNA in
     the replication cycle of cells.
     [PJC]