1 definition found mooresboro - U.S. Gazetteer (1990) : Mooresboro, NC (city, FIPS 44160) Location: 35.29906 N, 81.69956 W Population (1990): 294 (144 housing units) Area: 4.6 sq km (land), 0.0 sq km (water) Zip code(s): 28114